Dr. Md. Mizanur Rahman

Associate Professor

 

EDUCATION

2007-Feb. 2010           Doctor of Philosophy (Ph.D), Chonbuk National University, Republic of    Korea

Graduate School of Veterinary Medicine

Major: Pharmacology and Toxicology

2005-2006    Master of Science (Department of  Pharmacology), Bangladesh Agricultural University, Bangladesh

Major: Veterinary Pharmacology and Toxicology

Name of Degree: MS in Pharmacology

1998-2001      Graduated from Bangladesh Agricultural University, Bangladesh

Major: Veterinary science

Name of Degree: Doctor of Veterinary Medicine (DVM)

1995- 1997 Higher Secondary Education, Government Lalon Shah College, Horinakundu, Jhenaidah, Bangladesh

Name of Degree: Higher Secondary Certificate (HSC)

1990- 1995   Secondary Education, Bhawanipur Secondary School, Horinakundu, Jhenaidah, Bangaladesh

Name of Degree: Secondary School Certificate (SSC)

1985-1990    Primary/Elementary Education

LANGUAGE OF COMMUNICATION

 1) Bengali – native language – excellent in reading, writing, speaking

2) English – 2nd Language and Medium of Education – Good in reading, writing, speaking

 SCHOLARSHIPS

 i) 2nd Stage Brain Korea -21 (BK-21) Research Scholarship (March, 2007-February 2010)

ii) World Assembly of Muslim Youth (WAMY) -From-2007

iii) Scholarship From Chonbuk National University

iv) Ontario Heart and Stroke Foundation, University of western ontario, Canada 2010-2012

 FELLOWSHIPS AND JOB EXPERIENCE

July 2012 to Present: Assistant Professor, Department of physiology and Pharmacology, Faculty of Veterinary Medicine and Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur-1706, Bangladesh

 

September 2010 to March 2012:          Post Doctoral Fellow, Department of Medicine, University of  Western Ontario, London, Ontario , Canada.

April 2010 to August 2010      Post Doctoral Fellow, Center for the Healthcare Technology Development, Chonbuk National University, Republic of Korea

March 2007 to Feb. 2010        Research assistant of 2nd stage Brain Korea 21 project, Dept of Pharmacology Chonbuk National University, South Korea and Toxicology, College of Veterinary Medicine,

August 2003 to Sep. 2006.       Technical Manager and Veterinary Service, Techno-Drugs Pharmaceutical Company, Dhaka, Bangladesh.

TEACHING ASSISTANCE

– 2007-2009       Experimental Methods;

–  For freshmen & sophomores at the College of Veterinary Medicine, Chonbuk National University

–  Methods of restraining, treating, rearing, injection, anesthesia and operation in laboratory animals

–  Methods of blood and sample collections

–  Toxicity test

– Several laboratory techniques

– In vivo and In vitro experimental techniques

RESEARCH INTERESTS

  • Cardiac-hypertrophy, Infarction, Ischemia/Reperfusion injury, hypertension and Vascular injury and remodeling, electrophysiology of the heart
  • Cardiovascular pharmacology and toxicology, ion channel and receptors
  • Cardiovascular disorder secondary to chronic kidney disease
  • Magnesium and Calcium channel focusing cardiovascular disease
  • Neurodegenerative disease following brain injury/stroke – rat/mouse model

 TECHNICAL EXPERIENCE FOR RESEARCH

TRAINING Teaching Methods, Learning Assessment and Curriculum Development

BSMR Agricultural University, Salna, Gazipur-1706, Bangladesh

 

Biosafety Refresher Training, The University of Western Ontario, Human Resources, Occupational Health and Safety. Section Instructor: Jennifer Stanley, Ann C. Jones, Emily Gray.

 

WHIMS Training, The University of Western Ontario, Human Resources, Occupational Health and Safety. Section Instructor: Anne Marie McCusker, Ann C. Jones

 

Training Course “ Guide for the care and use of Laboratory animal” University of  Western Ontario Animal Care and Use Committee

 

Training Course “ Guide for the care and use of Laboratory animal” Chonbuk National University Institutional Animal Care and Use Committee of Laboratory animal

 

Breeding, sampling, and anesthesia of experimental animals (mouse, rats).

 
SKILLNESS i) ADI, BioPack and Labscisence system

Cardiac function/pressure volume loop, Invasive blood pressure recording of rat and mice

Hemodynamic recoding using micro sensor catheter and transducer system

Arterial, venous and cardiac catheterization and in vivo test

Electrocardiography/Electrophysiology in experimental animal (Endocardial and Surface)

ii) Langendorf system

Isolated heart perfusion, Isolated liver perfusion

iii) Vascular tension measurement with organ bath vascular ring by transducer system

iv). PTI system (Photon technology international)

Intracellular ions (Mg2+, Ca2+) measurement with lesser scanning fluorescence microscope.

v). NOVA stat profile

Blood ions measurements with ion selective electrodes

vi) Atomic Absorption spectrometry (Analab)

vii) Spectrophotometry

viii) H9C2 Cell line (Cardiomyocyte), Primary cardiomyocyte (Neonatal and adult) and vascular smooth muscle cell isolation and culture for in vitro experiment

ix) Western blotting and Image Analysis (Bio Rad), PCR methodology

x) General slide of tissue specimen and H-E stain, Von kossa staining for calcium, Serius Red and Masson trichrome staining for fibrosis, WGA staining for cell size measurement

xi) Several assay methods eg ELISA, LDH, SOD, MTT, Caspase -3 activity, Mitochondrial ROS measurement

xii) Transgenic mouse management and genotyping

 
 

OPERATION TECHNIQUES

  

Experimental surgical operations such as Pressure overload cardiac hypertrophy by transverse aortic banding, Myocardial infarction by LAD coronary artery occlusion, Left ventricular Ischemia-Reperfusion by thoracotomy, Arterial and Venous catherization, Middle cerebral artery occlusion by introducing monofilament nylon though internal carotid artery, Endovascular injury in mouse, 5/6 nephrectomy, Isolated working heart and liver perfusion (Rat), Arterial ring preparation and tension measurement.

 

Experimental disease models in mouse and rat

l  Cardiac hypertrophy induced by transverse aortic constriction

l  Ischemia-Reperfusion of left ventricle by LAD coronary artery occlusion

l  Myocardial infarction by LAD coronary artery ligation

l  Hypertension – animal model

l  Endovascular injury in mouse,

l  Focal brain ischemia by monofilamentus middle cerebral artery occlusion